Leading change in a volatile, uncertain and complex world


The pace of change in the life sciences industry has never been greater. Companies are under pressure to keep up with significant levels of market activity including mergers and acquisitions (M&A), technological advancement coupled with enhanced customer expectations, and heightened disruption from non-traditional competitors.

Mergers and acquisitions

For many organisations, M&A is a means of quickly gaining a competitive edge. The right opportunity will enable them to accelerate research and development (R&D) activities, while restocking their shrinking product pipelines.

Technological advancement

To stay ahead of the curve and satisfy customer expectations, organisations need to be able to deliver tailored therapies based on an understanding of their end users for which technology is vital.

Non-traditional competitors

Disruption from non-traditional competitors is increasing the size and complexity of the industry. This is driving organisations to shift from a more focused portfolio approach to patient-centric innovation.


Our experienced team will work with you to set up and deploy complex programmes to help drive the rate of change within your organisation. Through collaborative design and the re-engineering of your operational improvement programmes, your organisation can shift its focus to deliver on patient and customer demands. We can also help you learn from the agility of your smaller competitors, enabling you to diversify your offering and be considered a non-traditional competitor.

Digital Transformation

Uncover your strategic digital choices, define your strategies and deliver value from digital investments. We couple digital delivery expertise with strategic consulting knowledge to deliver meaningful and lasting digital change.


Making Strategy Happen

Translate your strategy into a meaningful portfolio of change to deliver it quickly, cost-effectively and with minimal disruption to your consumers and end-users.


Target Operating Model

Constant change in the sector means traditional operating models are no longer enough. We can help you build an agile operating model that withstands the impact of organisational change and considers the implications of M&A.


People Change

As the scale and complexity of the change portfolio increases, people need to feel part of the journey very quickly and, where necessary, lead on the change. We can support you make the right interventions to help your people, suppliers, partners and customers navigate the pace of change.



We are privileged to be working with some of the UK’s largest and most innovative life sciences organisations on their complex change programmes. You can read some of them here.

People analytics operating model for a FTSE 100 pharmaceutical company

Designing a new people analytics operating model, covering people, process, tools and technology, with a new data initiative prioritisation framework.

Global joint venture integration: sales capability organisation design

Our client was undertaking the acquisition of another major retailer. This required a programme of work to optimise both teams for success including the design of a new commercial operating model, organisation structure and way of working.

Embedding change into a FTSE 100 organisation’s DNA

Responding to cost pressures, digital advancements and regulatory change, our client had a challenging global transformation portfolio to deliver.


If you would like to speak to Gate One about how we can support you with your transformation journey please contact Simon Dennis, life sciences lead, on

Simon Dennis
Simon DennisSimon Dennis| Partnerlinkedin icon

A founding partner of Gate One, Simon has spent over 15 years leading and delivering change programmes at many of the UK’s leading businesses and government bodies. He has worked extensively in healthcare and pharmaceuticals and delivered strong year-on-year business development growth while managing engagement teams on high-profile transformation programmes for his clients.

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Gemma Sarjeant
Gemma SarjeantGemma Sarjeant| Principallinkedin icon

Gemma is an experienced consultant with a focus on complex project and programme management, M&A integration/separation, supply chain and operations. She has led numerous projects for a variety of FTSE 100 clients and recently undertook the role of programme manager for the Brexit implementation programme at a major pharmaceutical company.

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